Seward B Rutkove Selected Research

Therapeutics

3/2021	Antisense oligonucleotide and adjuvant exercise therapy reverse fatigue in old mice with myotonic dystrophy.
1/2020	The Value of Imaging and Composition-Based Biomarkers in Duchenne Muscular Dystrophy Clinical Trials.
10/2019	Electrical Impedance Methods in Neuromuscular Assessment: An Overview.
1/2019	Separation of Subcutaneous Fat From Muscle in Surface Electrical Impedance Myography Measurements Using Model Component Analysis.
5/2017	Electrical impedance myography for assessment of Duchenne muscular dystrophy.
9/2016	Quantitative Ultrasound Assessment of Duchenne Muscular Dystrophy Using Edge Detection Analysis.
3/2016	The neuromuscular impact of symptomatic SMN restoration in a mouse model of spinal muscular atrophy.
2/2016	ALS biomarkers for therapy development: State of the field and future directions.
2/2015	Composite biomarkers for assessing Duchenne muscular dystrophy: an initial assessment.
6/2014	Electrical impedance myography for the in vivo and ex vivo assessment of muscular dystrophy (mdx) mouse muscle.

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Seward B Rutkove Research Topics

Disease

14	Disease Progression 10/2019 - 11/2007
13	Amyotrophic Lateral Sclerosis (Lou Gehrig's Disease) 01/2021 - 11/2007
9	Duchenne Muscular Dystrophy (Muscular Dystrophy, Becker) 01/2020 - 07/2014
6	Neuromuscular Diseases (Neuromuscular Disease) 01/2018 - 02/2005
5	Spinal Muscular Atrophy (Progressive Muscular Atrophy) 12/2017 - 01/2011
3	Muscular Dystrophies (Muscular Dystrophy) 09/2017 - 06/2014
3	Pain (Aches) 07/2016 - 10/2009
3	Diabetic Neuropathies (Diabetic Neuropathy) 01/2011 - 01/2009
2	Fatigue 01/2022 - 03/2021
2	Muscular Diseases (Myopathy) 01/2019 - 09/2016
2	Myositis (Idiopathic Inflammatory Myopathies) 01/2018 - 07/2002
2	Hypothyroidism 06/2012 - 07/2002
1	Muscular Atrophy (Muscle Atrophy) 12/2021
1	Lewis Lung Carcinoma 12/2021
1	Myotonia 03/2021
1	Myotonic Dystrophy (Dystrophia Myotonica) 03/2021
1	Contracture 01/2020
1	Inclusion Body Myositis 01/2020
1	Inflammation (Inflammations) 01/2019
1	Brain Neoplasms (Brain Tumor) 01/2019
1	Hypertrophy 07/2018
1	Edema (Dropsy) 01/2018
1	Rare Diseases (Rare Disease) 12/2017
1	Atrophic Muscular Disorders 09/2017
1	Neurodegenerative Diseases (Neurodegenerative Disease) 02/2016
1	Mitochondrial Diseases (Mitochondrial Disease) 05/2013
1	Neuroinflammatory Diseases 05/2013
1	Peripheral Nervous System Diseases (PNS Diseases) 08/2012
1	Radiculopathy (Radiculopathy, Cervical) 08/2012
1	Hypertension (High Blood Pressure) 12/2010
1	Polyneuropathies (Polyneuropathy) 12/2010
1	Muscle Cramp (Cramp) 10/2009
1	Neuralgia (Stump Neuralgia) 10/2009
1	Polymyositis 07/2002
1	Renal Cell Carcinoma (Grawitz Tumor) 07/2002
1	Myasthenia Gravis 07/2002
1	Type 1 Diabetes Mellitus (Autoimmune Diabetes) 07/2002
1	Vitiligo 07/2002
1	Melanoma (Melanoma, Malignant) 07/2002

Drug/Important Bio-Agent (IBA)

22	Biomarkers (Surrogate Marker)IBA 01/2020 - 12/2011
4	ElementsIBA 01/2018 - 01/2011
3	Antisense OligonucleotidesIBA 03/2021 - 01/2016
3	Pharmaceutical PreparationsIBA 01/2020 - 06/2012
3	MyostatinIBA 07/2018 - 01/2015
2	Proteins (Proteins, Gene)FDA Link 12/2021 - 03/2016
2	Dexamethasone (Maxidex)FDA LinkGeneric 12/2021 - 01/2019
2	Adrenal Cortex Hormones (Corticosteroids)IBA 01/2019 - 07/2002
2	Biological ProductsIBA 03/2016 - 02/2016
1	Explosive Agents (Explosives)IBA 01/2022
1	Estrogens (Estrogen)FDA Link 12/2021
1	ezogabine (retigabine)IBA 01/2021
1	Mexiletine (Mexitil)FDA LinkGeneric 01/2021
1	CarrageenanIBA 01/2019
1	Superoxide DismutaseIBA 11/2018
1	SteroidsIBA 09/2017
1	DystrophinIBA 01/2017
1	Immunosuppressive Agents (Immunosuppressants)IBA 07/2016
1	salicylhydroxamic acid (SHAM)IBA 03/2016
1	RNA (Ribonucleic Acid)IBA 05/2013
1	Prostaglandins EIBA 01/2013
1	Riluzole FDA LinkGeneric 01/2013
1	Superoxide Dismutase-1IBA 01/2012
1	Anticonvulsants (Antiepileptic Drugs)IBA 01/2011
1	Thioctic Acid (Lipoic Acid)IBA 01/2011
1	Antidepressive Agents (Antidepressants)IBA 01/2011
1	Opioid Analgesics (Opioids)IBA 01/2011
1	Angiotensin IIIBA 12/2010
1	Topiramate (Topamax)FDA LinkGeneric 10/2009
1	Duloxetine Hydrochloride (Cymbalta)FDA Link 10/2009
1	Pregabalin (Lyrica)FDA Link 10/2009
1	Gabapentin (Neurontin)FDA LinkGeneric 10/2009
1	NAD (NADH)IBA 01/2009
1	2-methylcyclopentadienyl manganese tricarbonyl (MMT)IBA 11/2007
1	Insulin (Novolin)FDA Link 07/2002
1	Interleukin-2 (IL2)IBA 07/2002
1	AntigensIBA 07/2002
1	Cholinergic ReceptorsIBA 07/2002

Therapy/Procedure

15	Therapeutics 03/2021 - 07/2002
3	Transplantation 07/2016 - 06/2012
3	Electrodes (Electrode) 01/2016 - 02/2005
1	Exercise Therapy (Therapy, Exercise) 03/2021
1	Molecular Targeted Therapy 03/2021
1	Intramuscular Injections 01/2019
1	Drug Therapy (Chemotherapy) 01/2015
1	Stem Cell Transplantation 03/2014
1	Spinal Injections 06/2012
1	Plasmapheresis 07/2002